CinnaTropin is the brand name of recombinant growth hormone (somatropin). Each CinnaTropin pre-filled pen contains 5 or 10 mg of somatropin (somatropin injection) as ready-to-use solution. CinnaTropin is available in a pack containing 1 sterile pre-filled pen and patient information leaﬂet.
-CinnaTropin is indicated for the treatment of pediatric patients with growth failure due to inadequate secretion of endogenous growth hormone (GH).
-CinnaTropin is indicated for the treatment of pediatric patients with short stature associated with Turner syndrome.
-CinnaTropin is indicated for the treatment of pediatric patients with short stature associated with Noonan syndrome.
-CinnaTropin is indicated for the treatment of pediatric patients with short stature associated with Parder-Willi syndrome.
-CinnaTropin is indicated for the treatment of pediatric patients with short stature associated with chronic renal insufficiency.
-CinnaTropin is indicated for the treatment of pediatric patients who have Idiopathic Short Stature (ISS).
-CinnaTropin is indicated for children born small for gestational age (SGA) who failed to show catch-up growth by 4 years of age or later.
-CinnaTropin is indicated for the treatment of adults with childhood-onset or adult-onset growth hormone deficiency.
-you have a critical illness caused by certain types of heart or stomach surgery, trauma or breathing (respiratory) problems.
-you are a child with Prader-Willi syndrome who is severely obese or has breathing problems including sleep apnea (brieﬂy stop breathing during sleep).
-you have cancer or other tumors.
-you are allergic to somatropin or any of the ingredients in CinnaTropin.
-your healthcare provider tells you that you have certain types of eye problems caused by diabetes (diabetic retinopathy).
-you are a child with closed bone growth plates (epiphyses).
-Use with caution in diabetic patients. These patients may require adjustment of their doses of insulin and/or other hypoglycemic agents.
-Call your healthcare provider at once if you have pain in your knees or hips or limp in walking.
-Call your healthcare provider at once if you have a headache, nausea, vomiting, or visual change.
Tell your healthcare provider about all your other medicines, especially:
-birth control pills or hormone replacement therapy;
-insulin or oral diabetes medicine;
-a steroid (prednisone, dexamethasone, methylprednisolone, and others).
Other drugs may affect somatropin, including prescription and over-the-counter medicines, vitamins, and herbal products.
Your healthcare provider will prescribe the dose that is right for you.
Tell your healthcare provider if you are pregnant or plan to become pregnant during treatment or if you are breast-feeding a baby.
Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time. Call your healthcare provider if you miss a dose.
If you think there has been an overdose, call your poison control center or get medical care right away.
CinnaTropin is injected under the skin (subcutaneous). Read the detailed Instructions for Use.
Like all medicines, CinnaTropin can cause side effects, although not everybody gets them. Tell your healthcare provider or get medical help right away if you have any of the following signs or symptoms:
Edema, headache, paresthesia, hypothyroidism, nausea, vomiting, pain at injection site, injection site reaction, flatulence, abdominal pain, arthralgia, otitis, and upper respiratory tract infection.
These are not all the possible side effects of CinnaTropin.
-Keep CinnaTropin out of the reach of children.
-Do not use if the solution is cloudy, leaking, or has particles.
-Before you use CinnaTropin pens for the first time:
Store your new, unused CinnaTropin pen in a refrigerator between 2°C and 8°C (36°F to 46°F).
Do not freeze CinnaTropin.
Keep CinnaTropin away from direct light.
Do not use CinnaTropin that has been frozen or in temperatures warmer than 25°C (77°F).
Do not use CinnaTropin after the expiration date printed on the carton and the pen.
-After you use CinnaTropin pens and there is still medicine left:
Store remaining CinnaTropin in the refrigerator between 2°C and 8°C (36°F to 46°F) and use within 4 weeks,
or Store remaining CinnaTropin at room temperature no warmer than 25°C (77°F) and use within 3 weeks.